GUaRDIAN is a consortium of over 280 clinicians and researchers from over 60 medical and research centers making it one of the largest clinical genomics research networks in India

Read more about the programme in the recent overview
Human Genomics 13:52 (2019)

What is GUaRDIAN ?
  GUaRDIAN is a collaborative research programme towards understanding the genetic basis and molecular mechanisms underlying rare genetic disorders. We use the advanced sequencing technologies, extensive bioinformatics and animal models. Our collaborators include a large number of clinicians and scientists.

Genomics for Precision Medicine in India
Our collaborative network includes pioneers in personal genome sequencing and analysis in India, and the collaborative network brings together the enormous expertise in clinical assessment, genome sequencing, analysis and interpretation. 

Focus areas of Research and Cohorts
Our network encompasses a wide variety of clinical specialties. Our specialized cohorts and focused programmes include 
Dermatology and GenodermatosisNeurological disorders, 
Liver Diseases , Kidney Diseases,  Metabolic Diseases and 
Rare Blood Groups just to name a few. We are open to include more cohorts in collaboration with clinical groups.  Please contact us for more details.
How can we help you
If you are a Clinician or Researcher, you could collaborate with the network and participate in ongoing research initiatives. Please contact us for more details
Give to GUaRDIAN
We look forward to working with organisations to advance the cause of education, genetic testing and research. 


  • Personal genomics in clinical medicine : it is not in the future anymore Vinod Scaria and Sridhar Sivasubbu. The decade following the International human genome sequencing initiative, which drew the blueprint of the human genome, has seen tremendous advancements that has made genomics ...
    Posted Mar 13, 2016, 3:11 AM by Vinod Scaria
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The CSIR-IGIB Sanofi Genzyme Fellowship in Genomics for Medical Professionals aims to introduce fundamental aspects of genomics and molecular medicine to clinicians through short-term visit, interaction and hands-on training on specific aspects of genomics with the faculty at the CSIR-Institute of Genomics and Integrative Biology (CSIR-IGIB) in Delhi.> more

Events and CME Update

  • Genomics in Clinics - JIPMER Puducherry CME on Genomics and applications in Clinical Medicine28th January 2020Hands on Workshop on Exome Sequence Analysis and Interpretation for Medical Professionals28th and 29th January 2020
    Posted Nov 26, 2019, 2:22 AM by Vinod Scaria
  • Cafe Genomics - Tirunelveli Medical College Cafe GenomicsFor Faculty Members and ResidentsCME on Genomics and applications in Clinical MedicineHands on Workshop on Exome Sequence Analysis and Interpretation for Medical ProfessionalsFor Medical Students ...
    Posted Nov 26, 2019, 2:17 AM by Vinod Scaria
  • Genetic and Genomic Medicine in Maternal and Fetal Care 4th Annual Conference of 3MGM2019 on “Genetic and Genomic Medicine in Maternal and Fetal Care”Madras Medical Mission, ChennaiSeptember 13-15, 2019Workshops on “Prenatal Interphase Fluorescence in situ ...
    Posted Aug 26, 2019, 10:06 PM by Vinod Scaria
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Recent Publications

  • Chemical screens in a zebrafish model of CHARGE syndrome identifies small molecules that ameliorates disease like phenotypes in embryo CHARGE syndrome is an autosomal dominant congenital disorder caused primarily by mutations in the CHD7 gene. Using a small molecule screen in a zebrafish model of CHARGE syndrome, we identified ...
    Posted May 2, 2019, 3:04 AM by Vinod Scaria
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Genomics and Social Responsibility 
Listen to Dr Sridhar Sivasubbu in conversation with Mr. Biju Dharmapalan
In Media 

  • Genome sequencing by CSIR to help in Precision Medicine in India The Council for Scientific and Industrial Research has sequenced the entire genomes of 1008 Indians in six months, under a mission that was aimed at demonstrating capability and scalability of ...
    Posted Oct 31, 2019, 12:33 AM by Vinod Scaria
  • Workshop on Genomics in Clinical Medicine at Aster Medcity, Kochi A workshop on Genomics in Clinical Medicine was held at Aster Medcity. This workshop was conducted by researchers at the CSIR Institute of Genomics and Integrative Biology(CSIR IGIB), one ...
    Posted Jan 31, 2019, 1:12 AM by Vinod Scaria
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Genome sequencing: A solution to India's problem of rare genetic diseases (Economic Times Nov 02, 2019)