Pediatric Immune Disorders / Govt. Medical College Kozhikode

The Collaborative Programme on Pediatric Immune Disorders at Government Medical College Kozhikode is a collaborative initiative to provide holistic approach to patient care including diagnosis, management and prevention of Pediatric Immune Disorders with emphasis on Primary Immunodeficiency Disorders.

Department of Pediatrics
Government Medical College, Kozhikode
Kerala, IN


Primary Immunodeficiency Disorders 
Handbook for Patients & Families
Clinical Services
Pediatric Immune Disorder Clinic
Every Monday, at the OPD, IMCH, Govt. Medical College, Kozhikode

Genetic Services
Genetic Testing
BTK Hotspot Mutation Screening for X Linked Agammaglobulinemia
BTK Deletion Hotpsot using MLPA for X Linked Agammaglobulinemia
CD40L Hotspot Mutation Screening for Hyper IgM Syndrome
MVK Hotspot mutation screening for Hyper IgD Syndrome
Whole Exome / Whole Genome sequencing as part of ongoing Research
Genetic Counselling Services
Prenatal Testing
Amniocentesis and prenatal testing services
Newborn and Patient Screening
TREC/KREC assay for T/B cell defects (currently being implemented)

Upcoming Educational Programmes
November and December 2020 Online
Sunday, August 18, 2019, Govt. Medical College, Kozhikode, KERALA

Dr Geeta Govindaraj
Professor of Pediatrics
Principal Investigator
Ms Athulya EP
Junior Research Fellow

Govindaraj GM, Krishnakumar P, Scaria V, Athulya E, Ajithkumar VT, Dongre AR.
Building on an Ad Hoc Covid-19 Response to Enhance Community-based Care for Vulnerable Children in Kerala, India. 
NEJM Catal Innov Care Deliv. (2020) doi: 10.1056/CAT.20.0543.

Govindaraj GM, Jain A, Peethambaran G, Bhoyar R, Vellarikkal SK, Ganapati A, Sandhya P, Edavazhippurath A, Dhanasooraj D, Puthenpurayil JM, Chakkiyar K, Mishra A, Batra A, Punnen A, Kumar S, Sivasubbu S, Scaria V
Spectrum of clinical features and genetic variants in mevalonate kinase (MVK) gene of South Indian families suffering from Hyperimmunoglobulin D Syndrome 
PLoS ONE (2020)

Govindaraj GM, Ramya U, Raj R, Athulya EP, Jain A, Scaria V, Jayakrishnan MP, Sivasubbu S, Dhanasooraj D, Ajithkumar VT, Dongre AR, Krishnakumar P.
Parental Experience of Hematopoietic Stem Cell Transplantation for Children with Primary Immune Deficiency Disorders.
Indian J Pediatr. (2020) Oct 23. doi: 10.1007/s12098-020-03541-3. Online ahead of print.

Aluri J, Desai M, Gupta M, Dalvi A, Terance A, Rosenzweig SD, Stoddard JL, Niemela JE, Tamankar V, Mhatre S, Bargir U, Kulkarni M, Shah N, Aggarwal A, Lashkari HP, Krishna V, Govindaraj G, Kalra M, Madkaikar M
Clinical, Immunological, and Molecular Findings in 57 Patients With Severe Combined Immunodeficiency (SCID) From India.
Front Immunol. 2019 Feb 4;10:23.

Govindaraj GM, Riyaz A, Krishnan C, Scaria V.
Rapid Transition of Facial Features from Early to Mid - Adolescence in Autosomal Dominant Hyper IgE Syndrome with a STAT3 Variation.
Indian J Pediatr. 2018 Jul;85(7):595-596.

Govindaraj GM, Karuthedath Vellarikkal S, Jayarajan R, Ravi R, Verma A, Chakkiyar K, Jayakrishnan MP, Arakkal R, Raj R, Kunnaruvath R, Sivasubbu S, Scaria V
Case Report: Whole exome sequencing identifies variation c.2308G>A p.E770K in RAG1 associated with B- T- NK+ severe combined immunodeficiency
F1000Research 2017, 5:2532