Primary Immunodeficiency Disorders

The GUaRDIAN Programme on Primary Immunodeficiency Disorders is a collaborative initiative to provide holistic approach to patient care including genomic diagnosis, management and prevention of Primary Immunodeficiency Disorders.

Spotlight on Primary Immune Deficiency Disorders
Handbook for Clinicians (1st Edition 2019)

Primary Immunodeficiency Disorders 
Handbook for Patients & Families

Printable Poster on Primary Immunodeficiency
Printable poster for your clinic / educational activities
GUaRDIAN Network Centres
Collaborative Programme on Pediatric  Immune Disorders
Govt. Medical College Kozhikode, KERALA

Maulana Azad Medical College, DELHI
St Stephen's Hospital, DELHI
Super Specialty Pediatric Hospital and Postgraduate Teaching Institute NOIDA
All India Institute of Medical Sciences, DELHI

Dr. DY Patil Medical College Hospital and Research Centre, PUNE 

Educational Programmes
November and December 2020 Online
Update on Primary Immunodeficiency Disorders 
Sunday, August 18, 2019, Govt. Medical College, Kozhikode, KERALA

In News
Genome sequencing: A solution to India's problem of rare genetic diseases
Economic Times NOV 02, 2019
Govindaraj GM, Krishnakumar P, Scaria V, Athulya E, Ajithkumar VT, Dongre AR.
Building on an Ad Hoc Covid-19 Response to Enhance Community-based Care for Vulnerable Children in Kerala, India. 
NEJM Catal Innov Care Deliv. (2020) doi: 10.1056/CAT.20.0543.

Govindaraj GM, Ramya U, Raj R, Athulya EP, Jain A, Scaria V, Jayakrishnan MP, Sivasubbu S, Dhanasooraj D, Ajithkumar VT, Dongre AR, Krishnakumar P.
Parental Experience of Hematopoietic Stem Cell Transplantation for Children with Primary Immune Deficiency Disorders.
Indian J Pediatr. (2020) Oct 23. doi: 10.1007/s12098-020-03541-3. Online ahead of print.

Govindaraj GM, Jain A, Peethambaran G, Bhoyar R, Vellarikkal SK, Ganapati A, Sandhya P, Edavazhippurath A, Dhanasooraj D, Puthenpurayil JM, Chakkiyar K, Mishra A, Batra A, Punnen A, Kumar S, Sivasubbu S, Scaria V
PLoS ONE (2020)

Sharma P, Jain A, Scaria V
Genetic landscape of rare autoinflammatory disease variants in Qatar and Middle Eastern populations through the integration of genomic datasets
medRxiv (2020) .08.10.20171363; 
[This is a preprint and presently under peer review]

Sandhya P, Vellarikkal SK, Nair A, Ravi R, Mathew J, Jayarajan R, Kumar A, Verma A, Sivadas A, Danda D, Sivasubbu S*, Scaria V*
Int J Rheum Dis (2017) Nov;20(11):1770-1775. doi: 10.1111/1756-185X.13042.

Govindaraj GM, Karuthedath Vellarikkal S, Jayarajan R, Ravi R, Verma A, Chakkiyar K, Jayakrishnan MP, Arakkal R, Raj R, Kunnaruvath R, Sivasubbu S, Scaria V
Case Report: Whole exome sequencing identifies variation c.2308G>A p.E770K in RAG1 associated with B- T- NK+ severe combined immunodeficiency
F1000Research 2017, 5:2532

Govindaraj GM, Riyaz A, Krishnan C, Scaria V.
Rapid Transition of Facial Features from Early to Mid - Adolescence in Autosomal Dominant Hyper IgE Syndrome with a STAT3 Variation.
Indian J Pediatr. 2018 Jul;85(7):595-596.