The decade following the International human genome sequencing initiative, which drew the blueprint of the human genome, has seen tremendous advancements that has made genomics fast, cost-effective and therefore in some terms equitable. These approaches which enabled the improved scale, cost effectiveness and therefore its utility and implementation has been popularly dubbed Next Generation Sequencing (NGS) approaches. NGS approaches has the potential to tremendously revolutionize clinical medicine, as imaging has revolutionized clinical medicine almost a decade ago.