Research

The GUaRDIAN project is primarily focused on research, with the aim to decipher the genetic causes of rare genetic disorders. We use cutting-edge research methodologies including Next-Generation sequencing, Genotyping micro-arrays and extensive computational analysis towards shedding light into rare genetic variants causing disorders. 

We also extensively use model systems including zebrafish to model the disease towards providing insights into disease mechanisms which are extremely useful leads towards developing therapeutic strategies for such disorders.

Our team comprise of a bunch of researchers and clinicians who complement their skill-sets and knowledge towards realizing this goal. During this processes, we also develop novel methodologies and tools towards identifying genetic variants, understanding basic biology and potentially applying them in clinical settings. 

Recent Publications

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